Current Projects



There is a full collaboration between SCRC and different departments within Soroka University Medical Center. Here are some of SCRC's recentl active studies:

Medical Clowning
The use of humor is one of the milestones for "medical clowning". This profession, established in the late 20th century is now an integral part of hospitals in the Western world. Studies investigating the connection between humor and physical health were initiated in the late 70s, and in 40 years of perspective, it is known is that humor has many positive effects.
The primary objective of this study is to investigate the effects of the presence of clowns on a child’s postoperative pain levels as well as the anxiety levels of the child and the accompanying parent.

Tonsillectomy and Tonsillotomy in Children
The objective of this study is to evaluate the efficacy of tonsillotomy as compared of tonsillectomy in terms of the recurrence of obstructive sleep apnea symptoms at least one year post operation - To evaluate the safety of tonsillotomy as compared with tonsillectomy in terms of periprocedural complications and to assess the rate of tissue regrowth after tonsillotomy.

OSA
Obstructive sleep apnea (OSA), a risk factor for stroke is common following stroke, occurring in 60% to 96% of post-stroke patients in the setting of an acute stroke. Little is known about sleep apnea during the first post stroke night (FPSN), a potential therapeutic window for some patients, since using formal polysomnography is complicated and not feasible in the setting of acute stroke hospitalization. 
The primary objective is to examine prevalence of Sleep Apnea (Obstructive or Central) in post stroke patients during the immediate post stroke phase.

Predict Study
A number of diseases that affect the cardiovascular system emerge during pregnancy, a physiological state associated with elevated insulin resistance. Gestational diabetes mellitus is a risk factor for the development of type 2 diabetes while gestational hypertension is associated with an elevated risk of developing subsequent systemic hypertension. The third component of the metabolic syndrome associated with insulin resistance, i.e. dyslipidemia, is a well known cardiovascular risk factor. However lipid physiology and pathophysiology during pregnancy has not been studied extensively in large population-based cohorts. The main objective of the study is to strengthen and confirm the preliminary findings of elevated triglycerides and low HDL levels being associated with adverse pregnancy outcomes and elevated triglycerides and low HDL levels during the gestation are associated with a high risk of developing dyslipidemia and metabolic syndrome.

Sepsis Registry
Sepsis or “Blood poisoning” as it is sometimes known is a medical condition defined as a whole body infection caused by the presence of bacteria in the blood stream, and is an enduring source of illness and deaths in the general population. Despite the progress in early diagnosis and advanced treatment options, it continues to be a high-mortality-rate disease. As the populations of the Western world continue to age, sepsis is slowly becoming a major common pathway for end-of-life events. Patients with sepsis comprise 10-40% of all admissions to the intensive care units. However, despite sophisticated diagnostic and treatment modalities, the death rate from sepsis remains relatively constant or even increases.
Compared to heart diseases, sepsis epidemiology is not well researched. Contemporary large, population-based nation-wide studies are lacking, and long-term prognosis of sepsis is not well understood.
Our study is a multicenter population based study that is collecting data from 7 different hospitals and 8 Intensive Care Units around Israel in order to investigate the incidence, current therapeutic practices, outcomes, and health expenditures associated with sepsis hospitalizations in intensive care units.


Breast Cancer and Osteoporosis
Bone mineral density (BMD) is considered to be a marker for lifetime estrogen exposure. Some studies have suggested that a higher bone mass is associated with an increase in breast cancer risk. The proposed biological explanation is stimulating effects of estrogen on both trabecular bone and mammary cells.
The primary objective of this study is to assess whether bone density is associated with a risk of subsequent development of breast cancer.

Environment and Health in the Northern Negev
Natural soils in arid and semi-arid zones are source areas for air pollution through emissions of dust-sized particles to the atmosphere. Some soils yet pollute even more because of disturbance. Soil-derived airborne particles (SDAP) may contain organic matter or toxic chemicals. Although the association between environmental dust exposure and respiratory morbidity exists, the rudimentary understanding of the relationships between SDAP and chronic obstructive pulmonary disease (COPD), acute coronary syndrome (ACS), and thus, socio-economic consequences, dictates the need for innovative and interdisciplinary quantitative-research into these issues. The overall objective of this research is to explore the impact of chronic and acute exposure to SDAP on COPD and ischemic heart diseases (IHD) in space and time in the Northern Negev.

Diabetes
The blood glucose level of a patient arriveing at a hospital is an independent prognostic factor that impacts the results of many acute conditions. Moreover, hyperglycemia, even in patients without diabetes, has a negative impact on hospital course and outcome including complications, length of stay and a morbidity and mortality that is 3 fold compared to diabetic patients and 10 fold compared to the general population.
Glucose levels in hospitalized patients are influenced by many factors. Among them are previous glucose control, reason for hospitalization, nutritional status and degree of catabolism and food intake, medications including hypoglycemic drugs and other drugs including steroids. Additional important factors include the expertise of the medical staff in managing glucose levels during hospitalization.
The diabetes clinic at Soroka University Medical Center had put together a comprehensive program with the goal of improving the control of blood glucose levels in the hospital by means of increasing awareness of the problem and teaching practical techniques aimed at how to
achieve this.
The achievement of controlling blood glucose levels during hospitalization depends on pharmacological treatment and correct nutrition for the patients as well as preventing technical errors in blood glucose measurements and insulin injections. Therefore the goal of this study is to assess the effectiveness of this intervention
.

Leishmania
In Israel, Cutaneous leishmaniasis (CL) is caused mainly by L. major and L. tropica species. Parasitological examinations performed in laboratory at Soroka University Medical Center during the last decade indicate an increase in CL incidence in Southern Israel and increase in L tropica infection. The disease has spread to new areas previously known to be free of infection. In addition, more cases, resistant to available treatment have been demonstrated, probably due to L. tropica in this region.
Our purpose is  to assess the epidemiology of Leishmania infection in Southern Israel, identify spatial and temporal trends and changing distribution of Leishmania and to develop a rapid test allowing for real time precise diagnosis of Leishmania species.

Fracture Prevention
Osteoporotic fractures, including hip fractures, are common and a major health care issues worldwide, with increasing incidence with time.
Every fragility fracture signals increased risk of future fractures as well as risk of premature mortality. Osteoporotic fractures carry a major health care impact worldwide, manifest both in terms of early mortality, decreased quality of life and an economic burden. We assume that intervention with various forms of Fracture Liaison Service, will reduce fracture rates by 25% and will be cost-effective. Our goal is to create a pathway for successful implementation of a multifaceted intervention for prevention of recurrent fractures.
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